Germinal Centers: Gaining Strength from the Dark Side
نویسندگان
چکیده
منابع مشابه
Gaining strength and focus from hardship.
Three members of my family have been diagnosed with cancer in the past five years. During the fall of my freshman year of high school, my older brother was diagnosed with acute lymphocytic leukemia. His health began to deteriorate in August 2006. My mother would take him to the hospital weekly, insisting that the doctors run every test on her ill-ridden son. Chris's diagnosis in November 2006 a...
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Models for the development and function of germinal centers (GCs) have been so widely discussed in the original literature that they now appear in immunology textbooks. Unfortunately, many of the tenets of these models have not yet been subjected to adequate experimental scrutiny. Indeed, recent studies have called several of their principal assumptions into question. In addition, the term germ...
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I n 1995, when I left a faculty position at the University of Pennsylvania to join the fledgling bioinformatics unit at what was then SmithKline Beecham Pharmaceuticals, the friendly jibes by academic colleagues about ‘‘going over to the Dark Side’’ were, I suspect, only half in jest. There weren’t all that many of us practicing bioinformatics at that time, and there was genuine concern that a ...
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ژورنال
عنوان ژورنال: Immunity
سال: 2015
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2015.11.019